Database (PyCoMdb)
==================

PyCoMdb is divided into two files:

#. pycom.db: Database with protein annotation information (700MB)
#. pycom.mat: Coevolution matrices in HDF5 format (115GB)

Additionally, we provide the alignment files for each protein in the database. See: https://pycom.brunel.ac.uk/alignments/

.. warning::

   Downloading the full database (including the alignment files) requires 1.2TB of disk space.


Instructions
------------

Please download the files from: https://pycom.brunel.ac.uk/downloads/

The required files are:

   #. `pycom.db <https://pycom.brunel.ac.uk/downloads/pycom.db>`_ (to query the database)
   #. `pycom.mat <https://pycom.brunel.ac.uk/downloads/pycom.mat>`_ (to load the coevolution matrices)
   #. Please note that you can only access individual alignment files. Instructions on how to download the alignment files are available from the `tutorial <tutorials.html>`_.

.. _ref-querykw:

Query keywords
--------------

.. xlsx-table::
   :file: tables/Table1.xlsx
   :sheet: Sheet1
   :header-rows: 1